姓名：季敏
职称：副主任医师
个人简介：江苏南通人，医学博士。哈佛大学访问学者、美高梅MGM33999博士后。现任中华医学会眼科学分会青年委员、中国老年医学学会眼科分会青年委员、省医学会眼科学分会常委、省青年联合会委员、市医学会眼科学分会副主任委员、市医师协会眼科医师分会副会长。入选省“333高层次人才”、市“226高层次人才”培养计划。
专业研究领域：白内障、青光眼。
专著与论集：
(1) Zhang W, Wu A, Zhang G, Ding X, Kang L, Zhou T, Ji M, Guan H. Ubiquitination of Ku70 by Parkin promotes apoptosis of lens epithelial cells. FEBS J. 2023 Mar 31. Epub ahead of print.
(2) Wu A, Zhang W, Zhang G, Ding X, Kang L, Zhou T, Ji M, Guan H. Age-related cataract: GSTP1 ubiquitination and degradation by Parkin inhibits its anti-apoptosis in lens epithelial cells. Biochim Biophys Acta Mol Cell Res. 2023 Apr;1870(4):119450.
(3) Lin W, Luo J, Li P, Ji M, Guan H. Anterior vitreous detachment and retrolental material during cataract surgery: incidence and risk factors, with pathological evidence. J Cataract Refract Surg. 2023 Jun 1;49(6):578-583.
(4) Ren R, Zhang G, Yang W, Xie Y, Wei M, Guan H, Ji M. Concentrations of glucose metabolites in the aqueous humour of diabetic cataract eyes. Eur J Ophthalmol. 2023 Feb 22:11206721231156496.
(5) Zhang G, Kang L, Li P, Ran Q, Chen X, Ji M, Guan H. Genome-Wide Repertoire of Transfer RNA-Derived Fragments in a Mouse Model of Age-Related Cataract. Curr Eye Res. 2022 Oct;47(10):1397-1404.
(6) Ji M, Sun Q, Zhang G, Huang Z, Zhang Y, Shen Q, Guan H. Microglia-derived TNF-α mediates Müller cell activation by activating the TNFR1-NF-κB pathway. Exp Eye Res. 2022 Jan;214:108852.
(7) Geng W, Lin W, Song P, Zhang M, Wu J, Su S, Yuan Y, Ji M, Guan H. Effect of Anterior Chamber Instability during Phacoemulsification Combined with Intraocular Lens Implantation. J Ophthalmol. 2022 Feb 23;2022:2848565.
(8) Song P, Li P, Geng W, Qin M, Su S, Zhou T, Yuan Y, Zhang G, Wu J, Ji M, Guan H. Cytokines possibly involved in idiopathic epiretinal membrane progression after uncomplicated cataract surgery. Exp Eye Res. 2022 Apr;217:108957.
(9) Wei M, Chen LM, Huang ZY, Zhang GW, Guan HJ, Ji M. Expression profile analysis to identify potential gene changes induced by dexamethasone in the trabecular meshwork. Int J Ophthalmol. 2022 Aug 18;15(8):1240-1248.
(10) Zhang Y, Xu Y, Sun Q, Xue S, Guan H, Ji M. Activation of P2X7R- NLRP3 pathway in Retinal microglia contribute to Retinal Ganglion Cells death in chronic ocular hypertension (COH). Exp Eye Res. 2019 Nov;188:107771.
(11) Ji Z, Xie Y, Guan Y, Zhang Y, Cho KS, Ji M, You Y. Involvement of P2X7 Receptor in Proliferation and Migration of Human Glioma Cells. Biomed Res Int. 2018 Jan 9;2018:8591397.
主要科研项目
主持国家自然科学基金两项、中国博士后及江苏省博士后科研面上资助一等资助等多项科研项目。
讲授课程
眼科学
指导研究生情况
已毕业硕士生7名；在读硕士生10名。