姓名：顾亚云
职称：讲师
个人简介：江苏南通人，理学博士。
专业研究领域：泛素化系统、耐药机制、膜蛋白功能等基础医学研究。
专著与论集：
1. Kun Zhong, Xiaojun Liu, Weihua Ding, Lizhong Peng, Xuhui Zeng*, Yayun Gu*. TRAF inhibition drives cancer cell apoptosis and improves retinoic acid sensitivity in multiple cancers models. Discover Oncology. 2023, 14(1): 117.
2. Yayun Gu*, Kun Zhong, Lizhong Peng, Weihua Ding, Xuhui Zeng*. TRAF4 silencing induces cell apoptosis and improves retinoic acid sensitivity in human neuroblastoma. Neurochemical Research. 2023, 48(7): 2116-2128.
3. Yayun Gu*, Lizhong Peng, Weihua Ding, Yang Wang, Xuhui Zeng*. An ultrasensitive FRET-based fluorescent low molecular weight heparin nanoprobe for quantifying heparanase activity. Talanta. 2023, 254: 124207.
4. Lixuan Wei, Huanyao Gao, Jia Yu, Huan Zhang, Thanh Thanh L. Nguyen, Yayun Gu, Marie R. Passow, Jodi M. Carter, Bo Qin, Judy C. Boughey, Matthew P. Goetz, Richard M. Weinshilboum, James N. Ingle, and Liewei Wang*. Pharmacological targeting of androgen receptor elicits context-specific effects in estrogen receptor-positive breast cancer. Cancer research. 2023, 83(3): 456-470.
5. Yayun Gu, Huanyao Gao, Huan Zhang, August John, Xiujuan Zhu, Suganti Shivaram, Jia Yu, Richard M Weinshilboum, Liewei Wang*. TRAF4 hyperactivates HER2 signaling and contributes to Trastuzumab resistance in HER2-positive breast cancer. Oncogene. 2022, 41(35): 4119-4129.
6. Sisi Qin, Huanyao Gao, Wootae Kim, Huan Zhang, Yayun Gu, Krisshna R Kalari, Jason P Sinnwell, Jodi A Scholz, Fang Xie, Ping Yin, Jia Yu, Bo Qin, Yongxian Zhuang, Lixuan Wei, Winston Tan, Alan H Bryce, Richard M Weinshilboum, Liewei Wang. Biomarkers for Predicting Abiraterone Treatment Outcome and Selecting Alternative Therapies in Castration-Resistant Prostate Cancer. Clinical pharmacology and Therapeutics. 2022, 111(6): 1296-1306.
主要科研项目
主持多项省部级以上科研项目，其中包括国家自然科学青年基金项目1项，江苏省基础研究计划青年基金项目1项、参与多项国家自然科学面上基金项目。
讲授课程
中医食疗学、人文与医学