姓名：毛立明
职称：教授
个人简介：山东广饶人，理学博士。
专业研究领域：基础医学、免疫学。
专著与论集：
1. Mao L, Kitani A, Hiejima E, Montgomery-Recht K, Zhou W, Fuss IJ, Wiestner A, Strober W#. Bruton tyrosine kinase deficiency augments NLRP3 inflammasome activation and causes IL-1β-mediated colitis. J Clin Invest，2020 Apr 1;130(4):1793-1807
2. Mao L, Kitani A, Similuk M, Oler AJ, Albenberg L, Kelsen J, Aktay A, Quezado M, Yao M, Montgomery-Recht K, Fuss IJ, Strober W#. Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's disease. J Clin Invest. 2018 May 1;128(5):1793-1806.
3. Xu Q, Sun W, Zhang J, Mei Y, Bao J, Hou S, Zhou X, Mao L. Inflammasome-targeting natural compounds in inflammatory bowel disease: Mechanisms and therapeutic potential. Front Immunol. 2022 Aug 24;13:963291.
4. Meng J, Li N, Liu X, Qiao S, Zhou Q, Tan J, Zhang T, Dong Z, Qi X, Kijlstra A, Mao L, Yang P, Hou S. NLRP3 attenuates intraocular inflammation by inhibiting AIM2 mediated pyroptosis through the P-SIK1/SREBF1 pathway. Arthritis Rheumatol. 2022 Dec 18.
5. Mao L, Dhar A, Meng G, Fuss I, Montgomery-Recht K, Yang Z, Xu Q, Kitani A, Strober W. Blau syndrome NOD2 mutations result in loss of NOD2 cross-regulatory function. Front Immunol. 2022 Sep 15;13:988862.
主要科研项目
主持多项省部级以上科研项目，其中包括国家自然科学基金项目3项和江苏省自然科学基金面上项目1项。
讲授课程
医学免疫学
指导研究生情况
已毕业硕士生1名；在读博士生1名，硕士生6名。